How our body clocks can make or break our health

On December 14, 2018, Posted by , In Buzz, By ,,, , With No Comments

As our lifestyles become increasingly demanding, we build our lives around artificially divided days and nights that accommodate the need to work night shifts, stay up all night, or travel between continents. But this impacts our natural body clocks, with unwanted consequences. New research homes in on how disruptions to…

Body clock disruptions may be an early sign of Alzheimer's

On January 30, 2018, Posted by , In Buzz, By ,,,,, , With No Comments

New research published in JAMA Neurology suggests that those people whose memory is intact and who do not show any signs of Alzheimer’s can have disrupted circadian rhythms — which may be a very early sign of Alzheimer’s. Napping during the day may disrupt the sleep/wake cycle in seniors. This…

Later circadian timing of food intake is associated with increased body mass index

On September 25, 2017, Posted by , In Buzz, By ,,,,,,,,, , With No Comments

Weight gain and obesity has been described as an epidemic and a complex problem in the United States. Previous research has linked poor diet to weight gain and high body fat, and eating later in the day has also been described as a risk factor for weight gain; however, the…

Controlling the body clock

On January 2, 2017, Posted by , In Buzz, By ,, , With No Comments

A new study from the laboratory of Hiroki Ueda at the RIKEN Quantitative Biology Center investigates circadian timekeeping with a novel approach to creating genetic knock-out rescue mice. Published in Molecular Cell, the study shows how this technique was used to quickly create numerous mouse lines, each with different…

Why you're stiff in the morning: Your body suppresses inflammation when you sleep at night

On August 10, 2016, Posted by , In Buzz, By ,,,,,,, , With No Comments

New research published online in The FASEB Journal, describes a protein created by the body’s “biological clock” that actively represses inflammatory pathways within the affected limbs during the night. This protein, called cryptochrome, has proven anti-inflammatory effects in cultured cells and presents new opportunities for the development of drugs…

Weight loss through diet changes can improve sleep at any body weight, says Penn study

On December 17, 2015, Posted by , In Buzz, By ,,,,,,,,,, , With No Comments

Weight loss due to dietary changes can improve sleepiness at any weight, says a study published by researchers from the Perelman School of Medicine at the University of Pennsylvania this month in the journal Sleep. The findings offer new insights into how weight fluctuations impact numerous aspects of sleep…

Cell's waste disposal system regulates body clock proteins

On October 7, 2015, Posted by , In Buzz, By ,,,,,,, , With No Comments

New way to identify interacting proteins could identify potential drug targets Rhythmic expression of key genes is essential for maintaining proper timekeeping of the body’s clock. In addition, rhythmic degradation of clockwork proteins is also crucial. However, surprisingly, researchers know little about these specific processes. A new Penn-led…

Scientists discover body clock switch

On October 5, 2015, Posted by , In Buzz, By ,,,, , With No Comments

Circadian rhythms enable all living beings to coordinate with the daily cycle, but how the body clock keeps accurate time, or how its malfunction affects people with sleep disorders, is not fully understood. Now, scientists say that a molecular “phosphoswitch” may provide the key. New clues to the body clock…

Keeping the body ticking

On October 4, 2015, Posted by , In Buzz, By ,, , With No Comments

Tick tock. Tick tock. A team of scientists from Duke-NUS Graduate Medical School Singapore (Duke-NUS) and the University of Michigan at Ann Arbor have discovered a molecular switch that regulates the body’s circadian clock and allows it to keep time. This switch could be a potential drug target to treat…

How an evening coffee can disrupt our body clock

On September 24, 2015, Posted by , In Buzz, By ,,,, , With No Comments

It is well known that drinking coffee at night can keep people awake, but scientists from the Medical Research Council Laboratory of Molecular Biology in the UK and the University of Colorado have made a discovery that may hold the key to how caffeine consumption affects the underlying body clock….